На базе ГУ “Института неврологии, психиатрии, наркологии и медицинской психологии НАМН Украины” было проведено открытое сравнительное исследование эффективности комплексного применения эдаравона, фиксированной комбинации L-аргинина и L-карнитина, ксилитол-содержащего раствора у 30 пациентов с неврологическими нарушениями в постковидном периоде. Группу сравнения составили 30 пациентов, которые получали стандартное базовое лечение. Проведенное лечение в основной группе уменьшило проявления выраженности астении, улучшило показатели качества жизни.

У постковидных пациентов с неврологическими осложнениями сывороточные уровни провоспалительных маркерных цитокинов IL-6 и VEGF были повышенными. Добавление к базовой терапии Ксаврона, Тивореля и Ксилата обусловило снижение уровней IL-6 и VEGF, что дает возможность предположить противовоспалительное влияние предложенной схемы лечения. Эффективность и безопасность синдромно-патогенетического комплекса определяет перспективу его назначения для лечения пациентов с неврологическими постковидными нарушениями.

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Ключевые слова: едаравон; лечение; лікування; неврологические нарушения; пандемія COVID-19; постковидный синдром; постковідний синдром

Автора: Мищенко Т.С., Мищенко В.Н., Соколик В.В., Фисенко А.В., Здесенко И.В. Харьковский национальный университет имени В.Н. Каразина, г. Харьков, Украина ГУ «Институт неврологии, психиатрии и наркологии Национальной академии медицинских наук Украины», г. Харьков, Украина

Опубликовано: Международный неврологический журнал, Том 17, N 6, 2021