Effect of a Novel Free Radical Scavenger, Edaravone (MCI-186), on Acute Brain Infarction
Edaravone, a novel free radical scavenger, demonstrates neuroprotective effects by inhibiting vascular endothelial cell injury and ameliorating neuronal damage in ischemic brain models. The present study was undertaken to verify its therapeutic efficacy following acute ischemic stroke. We performed a multicenter, randomized, placebo-controlled, double-blind study on acute ischemic stroke patients commencing within 72 h of […]
Posted: Cerebrovasc Dis 2003
When stroke
Медикаменти для лікування підбирають в залежності від типу інсульту та стану пацієнта під час надходження до лікарні. У схемах використовують таблетки, уколи та крапельниці. Починати лікування слід якомога раніше. Оптимальний термін – перші години з моменту появи симптомів. Препарати, які застосовуються, можна розділити на три великі групи: Медикаменти для гострого періоду. Вони використовуються у перші […]
Acute ischemic stroke: revealing the maximum possibilities of pharmacotherapy
Materials of the XXI International Scientific and Practical Conference “Interdisciplinary Issues in Modern Neurology”, April 22-24, Truskavets, Ukraine. Much attention was paid during the event to the problematic aspects of managing patients with acute ischemic stroke. Within the framework of intensive therapy in cardioneurology a separate scientific symposium discussed the possibilities of modern pharmacotherapy for acute […]
Posted: Medical newspaper "Health of Ukraine", № 12 (457), 2019
Acute Kidney Injury and Edaravone in Acute Ischemic Stroke: The Fukuoka Stroke Registry
Background: A free radical scavenger, edaravone, which has been used for the treatment of ischemic stroke, was reported to cause acute kidney injury (AKI) as a fatal adverse event. The aim of the present study was to clarify whether edaravone is associated with AKI in patients with acute ischemic stroke. Methods: From the Fukuoka Stroke Registry database, 5689 consecutive […]
Posted: International Neurological Journal, №3 (105), 2019
The search for new methods and drugs to struggle with cerebral stroke and its complications
The scientific-practical conference “Opportunities and Achievements of Modern Pharmacotherapy in the Practice of a Neurologist” held in Kharkov on March 14-15, 2019. It was organized by Association of Neurologists, Psychiatrists and Narcologists of Ukraine, Institute of Neurology, Psychiatry and Narcology of the National Academy of Medical Sciences of Ukraine, Kharkiv National University named after V.N. […]
Posted: Health of Ukraine. Thematic issue "Neurology, Psychiatry, Psychotherapy" No. 2, 2019.